Emphysema lung condition characterized by abnormal permanent enlargement of air spaces distal to terminal bronchiole accompanied by destruction of their walls in the absence of obvious. The cardinal physiologic defect in emphysema is a decrease in elastic recoil. This leads to a decrease in maximal expiratory air, hyperinflation and air capture. Emphysema is usually the result of smoking, and a chronic progressive disease that eventually leads to disability and premature death. It is currently estimated at 2 million adults in the United States and with other forms
(COPD) is 90 000 deaths annually. Emphysema is characterized by loss of elasticity (increased pulmonary compliance) of lung tissue caused by the destruction of structures feeding the alveoli, in some cases due to the action of alpha-1-antitrypsin. This leads to the small airways to collapse during forced expiration and alveolar styahivaemosti decreased. As a result, air flow and prevents the air is caught in a trap in the lungs, just like other obstructive lung diseases. Symptoms include shortness of breath on exertion and chest expanded. However, narrowing the airway is not always immediately fatal, and treatment. Symptoms of emphysema include selected lipped breathing, central cyanosis of fingers and clubs. Chest has a hyper-resonant percussion note, in particular, only the liver, and it is difficult to probe the top rate, as a result of hyperinflation. There may be decreased breath sounds and audible expiratory wheezing. In later stages of the disease, there are signs of fluid overload such as pitting peripheral devices. A person has ruddy complexion if there is a secondary polycythemia. Suffering, which store carbon dioxide in the 'fluttering' tremor (metabolic flap) at the wrist. Emphysema can be divided into primary and secondary. However, most often classified by location. Emphysema can be subdivided into panacinary and centroacinary (or panacinar and centriacinar or tsentrodolevaya and panlobular). Panacinary (or panlobular) emphysema due to destruction of alveoli, because of inflammation or deficiency of alpha-1-antitrypsin. It turns out that even in young adults who have chronic in nature.
Centroacinary (or tsentrodolevaya) emphysema due to destruction muchosis terminal bronchioli, due to chronic bronchitis. It occurs mainly in older people with a long history of smoking or passive smoking a last resort. Other types include distal ferruginous and irregular. A special type of congenital emphysema is lasix 4 mg partial (CLE). CLE leads to pererasshireniya of pulmonary compression shares and consequently other particles ipsilateral lung, and possibly the opposite of light. There bronchial narrowing through weak or absent bronchial. There may be congenital external compression, usually abnormally large pulmonary artery. It causes bronchial cartilage defects, making them soft and complex. CLE potentially reversible, but possibly life-threatening, leading to respiratory failure in newborns. Sources and ignore the information contained in Wikipedia (), CDC, NIH. .
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